Erza Scarlet - Fairy Tail
[ranking: 1]
Erza Scarlet of Fairy Tail has so many amazing abilities that if she were a D&D character the dungeon master would flip over the board in frustration. This formidable woman is an S-Class Mage of the Fairy Tail Guild. She not only boasts ridiculous magical abilities that include telekinesis, sword magic, and the ability to "requip" - to switch out armor and offensive tools at a lightning fast speed.
She's also scary strong, super fast, and a master at archery, hand-to-hand combat, and swordsmanship.
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Akame - Akame Ga Kill!
[ranking: 2]
Akame of Akame ga Kill! is the strongest member of the Night Raid, a group focused on reconnaissance and assassination. Akame not only boasts superior swordsmanship, she also has some fascinating special abilities. She's immune to most poisons, allowing her to handle the poisonous blade Teigu.
She can move at Mach 1 - the velocity of sound. When Akame wants to kill someone, she can completely disguise her intentions and surprise her enemies. Defeating her is a challenge few people are equipped to meet.
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Nana Shimura - My Hero Academia
[ranking: 3]
It's hard to imagine that All Might of My Hero Academia ever had a mentor - he has such a powerful presence that it seems like he had to have come to it on his own. But All Might got both his powers and his heroic attitude from Nana Shimura, the seventh inheritor of One For All.
The power allows its users to stockpile their power, which allows for super strength, super speed, and other incredible abilities - but unless the user is physically strong enough to withstand it, the strain can tear the user apart. Nana boasts the same incredible strength as her protege All Might.
Izumi Curtis - Fullmetal Alchemist Brotherhood
[ranking: 4]
Fullmetal Alchemist Brotherhood's Izumi Curtis might call herself an ordinary housewife, but ordinary housewives typically aren't strong enough to beat up a bear. Despite her overwhelming physical prowess, Izumi is also a talented alchemist - she taught the Elric brothers nearly everything they know.
These talents are more impressive because Izumi severely damaged her organs when an attempt to bring her child back to life through alchemy went terribly wrong. Even when she's coughing up blood, she's still a formidable opponent.
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Tsunade - Naruto
[ranking: 5]
While there are a lot of badass women in Naruto, the most powerful is probably Tsunade. Not only does she have super strength so incredible that she was able to split the ground with a single finger, she also has impeccable chakra (energy) control, which he can use to perform Lightning, Fire, Water, Earth, and Yin and Yang based jutsu (techniques). This means that she has complete control over the elements and her own spiritual energy. She's so powerful that her attacks can even penetrate Susano-o, which is supposed to be an impenetrable defense.
That's not all - Tsunade is also a world-class healer who can not only cure just about any disease or injury in existence, but can also alter her appearance so that she appears eternally youthful. Tsunade is one shinobi you don't want to mess with.
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Android 18 - Dragon Ball Z
[ranking: 6]
Android 18 of Dragon Ball Z has so many incredible special abilities that describing them all would take longer than it takes Goku to finish a fight. She can fly, create explosions, shoot high energy beams, teleport, and generally beat the living snot out of anyone who dares to mess with her. What's more, her powerful personality demands obedience from even the strongest fighters in the Dragon Ball universe.
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Lucy - Elfen Lied
[ranking: 7]
You do not want to get on Lucy's bad side, but if you're any of the characters in Elfen Lied, you probably already have. Lucy can use "vectors" or invisible telekinetic arms, that can be incredibly powerful. These vectors are powerful enough to literally destroy the planet, and she's used them to kill over 9,000 people - but perhaps her most impressive ability is having a tragic enough backstory to make all those murders seem justifiable.
Shiro - Deadman Wonderland
[ranking: 8]
Deadman Wonderland features a terrifying little girl named Shiro. Like Lucy from Elfen Lied, she's been endlessly experimented on, and that experimentation has made her a formidable opponent. As a result of this experimentation, Shiro can rapidly regenerate her body when wounded, and she can use something called the branch of sin, which allows her to control her own blood and use it as a weapon. The branch of sin can also be turned into a deadly whip.
Shiro's abilities increase dramatically when her body is being controlled by the Wretched Egg, her alternate personality.
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Ryuko Matoi - Kill La Kill
[ranking: 9]
At the beginning of Kill la Kill, Ryuko Matoi doesn't know she has any special powers. Once she joins up with Senketsu, a sentient school uniform made with life fibers, a nearly immortal life form from space, she discovers her immense potential to kick butt. Later, it turns out that Ryuko doesn't actually need Senketsu to defeat her enemies - she herself is partially composed of life fibers.
These fibers not only grant her superhuman strength, they also allow her to easily heal even the most grievous of wounds.
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Kanade Tachibana - Angel Beats
[ranking: 10]
The last thing that anyone in the world of Angel Beats wants to hear is Kanade Tachibana's sweet little voice saying "hand sonic." When they hear that, they know they're going down. Kanade's job is to help smooth over the personal issues of the denizens of the afterlife, but after they declare war on her, she has to defend herself. To do so, she develops an array of superhuman abilities.
Hand Sonic actually includes several techniques, all of which involve fighting with handheld blades. She can also distort images, create painful high-frequency sound waves, create clones of herself, absorb those clones, sprout angel wings, create a drill-like blue light that destroys everything in its path, and more.
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Medaka Kurokami - Medaka Box
[ranking: 11]
Medaka Kurokami of Medaka Box is powerful to the point of absurdity. No one has ever been able to teach her anything, because she learns everything instantaneously. She can perfectly control every single movement in her body, even her own heartbeat. She's super strong, super fast, super flexible, and super hardy. She's an expert at countless forms of combat, and both humans and animals often feel compelled to obey her commands. She can even break the sound barrier.
What does Medaka do with all this incredible raw power? She tries her hardest to grant her classmate's wishes and help them with their problems. So not only is she crazy powerful, she's also super nice.
Madoka Kaname - Puella Magi Madoka Magica
[ranking: 12]
Arale Norimaki - Dr. Slump
[ranking: 13]
Known by some fans as One Punch Girl, the adorable Arale Norimaki of Dr. Slump is scary strong. She once split the earth in half by punching the ground, she's so fast that she can travel from Earth to Saturn in a few seconds, and can lift up to 100 tons. As if that wasn't enough, in a Dragon Ball Super cameo, she easily defeated both Goku and Vegeta, two of the most powerful anime characters of all time.
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