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Joseph M. Acaba (A)
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Loren Acton (A)
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James Adamson (A)
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Viktor M. Afanasyev (A)
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Aydyn Aimbetov, first cosmonaut by KazCosmos-selection in space (A)
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Thomas Akers (A)
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Toyohiro Akiyama, the first business-sponsored space traveler and the first Japanese person in space (A)
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Vladimir Aksyonov (A)
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Sultan Salman Al Saud, first Saudi Arabian in space, only royal person in space, first Middle Eastern person in space (A)
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Buzz Aldrin, flew on Apollo 11; second person to walk on the Moon (A)
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Aleksandr Panayotov Aleksandrov (A)
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Aleksandr Pavlovich Aleksandrov (A)
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Andrew M. Allen (A)
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Joseph P. Allen (A)
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Hazza Al Mansouri, first UAE astronaut (A)
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Scott Altman (A)
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William Anders, first Asian-born person in space (born in Hong Kong, but an American citizen) (A)
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Clayton Anderson (A)
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Michael P. Anderson (1959–2003), died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (A)
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(Claudie André-Deshays – see Claudie Haigneré) (A)
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Anousheh Ansari, fourth spaceflight participant and first female spaceflight participant, first woman of Muslim descent in space, and first Iranian in space (A)
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Dominic A. Antonelli (A)
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Jerome Apt (A)
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Lee Archambault (A)
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Neil Armstrong (1930–2012), flew on Apollo 11; first person to walk on the Moon (A)
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Richard R. Arnold (A)
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Oleg Artemyev (A)
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Anatoly Artsebarsky (A)
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Yuri Artyukhin (1930–1998) (A)
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Jeffrey Ashby (A)
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Oleg Atkov (A)
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Toktar Aubakirov, first Kazakh born person in space (A)
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Serena Auñón-Chancellor (A)
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Sergei Avdeyev (A)
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James Bagian, first Armenian in space (B)
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Ellen Baker (B)
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Michael Baker (B)
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Aleksandr Balandin (B)
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Michael Barratt (B)
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Daniel Barry (B)
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John-David F. Bartoe (B)
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Yuri Baturin, first Russian politician in space (B)
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Patrick Baudry, first African-born man and second Frenchman in space (B)
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Alan Bean (1932–2018), flew on Apollo 12; fourth person to walk on the Moon (B)
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Robert L. Behnken (B)
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Ivan Bella, first Slovak in space (B)
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Pavel Belyayev (1925–1970) (B)
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Georgi Beregovoi (1921–1995), earliest-born person to go into orbit (B)
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Anatoli Berezovoy (1942–2014) (B)
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Brian Binnie, second commercial (launched by a private company) astronaut; suborbital flight only (B)
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John Blaha (B)
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Michael J. Bloomfield (B)
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Guion Bluford, first African-American in space (B)
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Karol Bobko, first graduate of the United States Air Force Academy to become an astronaut (B)
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Eric A. Boe (B)
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Charles Bolden (B)
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Roberta Bondar, first Canadian woman in space (B)
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Andrei Borisenko (B)
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Frank Borman, commander of Apollo 8, the first spaceflight to orbit the Moon (B)
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Stephen G. Bowen (B)
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Kenneth Bowersox (B)
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Charles Brady (1951–2006) (B)
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Vance Brand (B)
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Daniel Brandenstein (B)
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Randolph Bresnik (B)
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Roy Bridges; became Director of the Kennedy Space Center in March 1997 (B)
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Curtis Brown (B)
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David M. Brown (1956–2003), died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (B)
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Mark Brown (B)
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James Buchli (B)
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Jay Buckey (B)
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Nikolai Budarin (B)
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Daniel Burbank (B)
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Daniel Bursch (B)
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Valery Bykovsky (B)
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Robert Cabana (C)
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Charles Camarda (C)
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Kenneth Cameron (C)
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Duane Carey (C)
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Scott Carpenter (1925–2013), a Project Mercury astronaut (C)
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Gerald Carr (C)
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Sonny Carter (1947–1991) (C)
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John Casper (C)
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Christopher J. Cassidy, 500th astronaut in space (C)
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Robert Cenker (C)
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Gene Cernan (1934–2017), flew on Apollo 17 (C)
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Gregory Chamitoff (C)
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Franklin Chang-Diaz, the only Costa Rican, first Hispanic-American in space, holder of the shared record of seven space flights (C)
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Kalpana Chawla (1961–2003), first Indian-American woman in space; died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (C)
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Maurizio Cheli (C)
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Chen Dong (C)
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Leroy Chiao (C)
-
Kevin Chilton (C)
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Jean-Loup Chrétien, first French person in space and first non-Soviet European to walk in space (C)
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Laurel B. Clark (1961–2003), died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (C)
-
Mary Cleave (C)
-
Jean-François Clervoy (C)
-
Michael Clifford (C)
-
Michael Coats (C)
-
Kenneth Cockrell (C)
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Catherine Coleman (C)
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Eileen Collins (C)
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Michael Collins, flew on Apollo 11; first Italian-born person in space (born in Rome to American parents) (C)
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Pete Conrad, (1930–1999), commanded Apollo 12 and the first Skylab mission (C)
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Gordon Cooper (1927–2004), first American to fly in space for over 24 hours (C)
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Richard Covey (C)
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Timothy Creamer (C)
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John Creighton (C)
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Robert Crippen, flew on STS-1 (C)
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Samantha Cristoforetti, first Italian woman in space (C)
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Roger Crouch (C)
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Frank Culbertson (C)
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Walter Cunningham, flew on Apollo 7 (C)
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Robert Curbeam (C)
-
Nancy J. Currie-Gregg (C)
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Nancy Jan Davis (D)
-
Lawrence J. DeLucas (D)
-
Frank De Winne (D)
-
Vladimir N. Dezhurov (D)
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Georgi Dobrovolski (1928–1971), died during Soyuz 11 (D)
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Takao Doi, first Japanese to walk in space (D)
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B. Alvin Drew (D)
-
Brian Duffy (D)
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Charles Duke, flew on Apollo 16 (D)
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Bonnie J. Dunbar (D)
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Pedro Duque, first Spaniard in space (D)
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Samuel T. Durrance (D)
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James Dutton (D)
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Lev Dyomin (1926–1998) (D)
-
Tracy Caldwell Dyson (D)
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Vladimir Dzhanibekov, first Uzbekistan-born man in space (D)
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Joe Edwards (E)
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Donn F. Eisele (1930–1987), flew on Apollo 7 (E)
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Anthony W. England (E)
-
Joseph H. Engle (E)
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Ronald Evans (1933–1990), flew on Apollo 17 (E)
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Reinhold Ewald (E)
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Léopold Eyharts (E)
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John Fabian (F)
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Muhammed Faris, first Syrian in space (F)
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Bertalan Farkas, first Hungarian in space (F)
-
Jean-Jacques Favier (F)
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Fei Junlong, flew on Shenzhou 6 (F)
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Konstantin Feoktistov (1926–2009) (F)
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Christopher Ferguson (F)
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Martin J. Fettman (F)
-
Andrew J. Feustel (F)
-
Anatoly Filipchenko (F)
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Michael Fincke (F)
-
Jack D. Fischer (F)
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Anna Fisher, first mother in space (F)
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William Frederick Fisher (F)
-
Klaus-Dietrich Flade (F)
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Michael Foale, holds the American and British Record for time spent in space at 374 days, 11 hours, 19 minutes (F)
-
Kevin A. Ford (F)
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Michael Foreman (F)
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Patrick Forrester (F)
-
Michael Fossum (F)
-
Stephen Frick (F)
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Dirk Frimout, first Belgian in space (F)
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Christer Fuglesang, first Swede in space (F)
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C. Gordon Fullerton (1936–2013) (F)
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Reinhard Furrer (1940–1995) (F)
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Satoshi Furukawa (F)
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Francis Gaffney (G)
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Yuri Gagarin (1934–1968), first person in space, first person to orbit the Earth (G)
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Ronald Garan (G)
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Dale Gardner (G)
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Guy Gardner (G)
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Jake Garn, a United States Senator and first politician in space (G)
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Marc Garneau, first Canadian in space (G)
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Owen Garriott (G)
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Richard Garriott, first second generation American in space; son of Skylab astronaut Owen Garriott (G)
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Charles Gemar (G)
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Michael Gernhardt (G)
-
Alexander Gerst (G)
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Edward Gibson (G)
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Robert L. Gibson (G)
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Yuri Gidzenko (G)
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Yuri Glazkov (1939–2008) (G)
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John Glenn (1921–2016), first American to orbit the Earth, the oldest person to make a spaceflight, and U.S. Senator (G)
-
Linda Godwin (G)
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Michael T. Good (G)
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Viktor Gorbatko (G)
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Richard Gordon (1929–2017), flew on Apollo 12 (G)
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Dominic Gorie (G)
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Ronald Grabe (G)
-
Georgi Grechko (G)
-
Frederick Gregory (G)
-
William Gregory (G)
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Stanley Griggs (1939–1989) (G)
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Virgil "Gus" Grissom (1926–1967), first NASA astronaut to go into space twice; first person to go into space twice in a capsule-type spacecraft; would have been the first person to fly three times; died in the Apollo 1 disaster (G)
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John Grunsfeld (G)
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Aleksei Gubarev (G)
-
Umberto Guidoni (G)
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Jügderdemidiin Gürragchaa, first Mongolian in space (G)
-
Sidney Gutierrez (G)
-
Chris Hadfield, first Canadian to walk in space (H)
-
Nick Hague (H)
-
Claudie Haigneré, first Frenchwoman in space (H)
-
Jean-Pierre Haigneré (H)
-
Fred Haise, flew on Apollo 13 (H)
-
James Halsell (H)
-
Kenneth Ham (H)
-
Lloyd Hammond (H)
-
Gregory Harbaugh (H)
-
Bernard Harris, first African-American to walk in space (H)
-
Terry Hart (H)
-
Henry Hartsfield (1933–2014) (H)
-
Frederick Hauck (H)
-
Steven Hawley (H)
-
Susan Helms (H)
-
Karl Henize (1926–1993) (H)
-
Thomas Hennen (H)
-
Terence Henricks (H)
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Mirosław Hermaszewski, first Pole in space (H)
-
José M. Hernández (H)
-
John Herrington, first Native American in space (H)
-
Richard Hieb (H)
-
Joan Higginbotham (H)
-
David Hilmers (H)
-
Kathryn Hire (H)
-
Charles Hobaugh (H)
-
Jeffrey Hoffman (H)
-
Michael S. Hopkins (H)
-
Scott Horowitz (H)
-
Akihiko Hoshide (H)
-
Millie Hughes-Fulford, first female payload specialist (H)
-
Douglas G. Hurley (H)
-
Rick Husband (1957–2003), died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (H)
-
James Irwin (1930–1991), flew on Apollo 15 (I)
-
Aleksandr Ivanchenkov (I)
-
Anatoli Ivanishin (I)
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Georgi Ivanov, first Bulgarian in space (I)
-
Marsha Ivins (I)
-
Sigmund Jähn (1937–2019), first German in space (J)
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Mae Jemison, first African-American woman in space (J)
-
Tamara E. Jernigan (J)
-
Brent W. Jett, Jr. (J)
-
Jing Haipeng (J)
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Gregory C. Johnson (J)
-
Gregory H. Johnson (J)
-
Thomas D. Jones (J)
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Leonid Kadenyuk, first Ukrainian in space since independence (K)
-
Alexandr Kaleri, first Russian in space since the fall of Communism (K)
-
Norishige Kanai (K)
-
Janet L. Kavandi (K)
-
James M. Kelly (K)
-
Mark Kelly (K)
-
Scott Kelly (K)
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Joseph Kerwin (K)
-
Yevgeny Khrunov (1933–2000) (K)
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Susan Kilrain (K)
-
Robert S. Kimbrough (K)
-
Leonid Kizim (1941–2010) (K)
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Pyotr Klimuk, first Belarusian in space (K)
-
Christina Koch, member of the first all-female EVA team (K)
-
Vladimir Komarov (1927–1967), died during Soyuz 1 (K)
-
Yelena Kondakova (K)
-
Dmitri Kondratyev (K)
-
Oleg Kononenko, first Turkmenistan-born man in space (K)
-
Timothy L. Kopra (K)
-
Mikhail Korniyenko (K)
-
Valery Korzun (K)
-
Oleg Kotov (K)
-
Vladimir Kovalyonok (K)
-
Konstantin Kozeyev (K)
-
Kevin Kregel (K)
-
Sergei Krikalev, six space flights; until 2015, held the record for longest total time in space: 803 days, 9 hours and 39 minutes (K)
-
Valeri Kubasov (1935–2014) (K)
-
André Kuipers (K)
-
Aleksandr Laveykin (L)
-
Guy Laliberté, first Canadian space tourist. (L)
-
Wendy Lawrence (L)
-
Vasili Lazarev (1928–1990) (L)
-
Aleksandr Lazutkin (L)
-
Valentin Lebedev (L)
-
Mark C. Lee (L)
-
David Leestma (L)
-
William B. Lenoir (L)
-
Alexei Leonov, first person to "walk in space" (to make an EVA) (1934-2019) (L)
-
Frederick W. Leslie (L)
-
Anatoli Levchenko (1941–1988) (L)
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Byron Lichtenberg, first NASA payload specialist (L)
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Don Lind (L)
-
Kjell N. Lindgren (L)
-
Steven Lindsey (L)
-
Jerry Linenger (L)
-
Richard Linnehan (L)
-
Gregory Linteris (L)
-
Liu Boming (L)
-
Liu Wang (L)
-
Liu Yang, first Chinese woman in space (L)
-
Paul Lockhart (L)
-
Yuri Lonchakov (L)
-
Michael Lopez-Alegria (L)
-
John Lounge (L)
-
Jack Lousma (L)
-
Stanley G. Love (L)
-
Jim Lovell, flew on Apollo 8, the first spaceship to orbit the Moon, and on Apollo 13 (L)
-
G. David Low (1956–2008) (L)
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Edward Lu (L)
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Shannon Lucid, first Asian-born woman in space; As of 2006[update], holder of the woman's spaceflight-duration record (L)
-
Vladimir Lyakhov (L)
-
Steven MacLean (M)
-
Sandra Magnus (M)
-
Oleg Makarov (1933–2003) (M)
-
Yuri Malenchenko (M)
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Franco Malerba, first Italian in space (Michael Collins was born in Rome, Italy in 1930, he has always been an American citizen, born of American parents.) (M)
-
Yury Malyshev (1941–1999) (M)
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Gennadi Manakov (M)
-
Musa Manarov, first Azerbaijan-born man in space (M)
-
Thomas H. Marshburn (M)
-
Michael Massimino (M)
-
Richard Mastracchio (M)
-
Thomas Kenneth "Ken" Mattingly II, flew on Apollo 16, STS-4, and STS-51-C (M)
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K. Megan McArthur (M)
-
William S. McArthur (M)
-
Jon McBride (M)
-
Bruce McCandless II (1937–2017) (M)
-
William C. McCool (1961–2003), died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (M)
-
Michael J. McCulley (M)
-
James McDivitt, flew on Apollo 9 (M)
-
Anne McClain (M)
-
Donald McMonagle (M)
-
Ronald McNair (1950–1986), died in the Space Shuttle Challenger disaster (M)
-
Carl Meade (M)
-
Jessica Meir, member of the first all-female EVA team, first Swedish woman in space, second Swede in space (M)
-
Bruce Melnick (M)
-
Pamela Melroy (M)
-
Leland D. Melvin (M)
-
Mike Melvill, first commercial (launched by a private company) astronaut; suborbital flight only (M)
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Ulf Merbold (M)
-
Ernst Messerschmid (M)
-
Dorothy Metcalf-Lindenburger (M)
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Alexander Misurkin (M)
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Edgar Mitchell (1930–2016), flew on Apollo 14 (M)
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Andreas Mogensen, first Dane in space (M)
-
Abdul Ahad Mohmand, first Afghan in space (M)
-
Mamoru Mohri (M)
-
Andrew Morgan (M)
-
Barbara Morgan (M)
-
Lee Morin (M)
-
Boris Morukov (M)
-
Beth Moses, first passenger of a commercial spaceflight; sub-orbital, has not met the FAI criterion of crossing the Kármán line (100km) (M)
-
Chiaki Mukai, first Japanese woman in space (M)
-
Richard Mullane (M)
-
Talgat Musabayev, first Kazakh citizen in space (M)
-
Story Musgrave (M)
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Steven R. Nagel (1946–2014) (N)
-
Bill Nelson, second politician in space (N)
-
George Nelson (N)
-
Rodolfo Neri Vela, first Mexican in space (N)
-
Paolo A. Nespoli (N)
-
James H. Newman (N)
-
Claude Nicollier, first Swiss in space (N)
-
Nie Haisheng, flew on Shenzhou 6 (N)
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Andriyan Nikolayev (1929–2004) (N)
-
Soichi Noguchi (N)
-
Carlos I. Noriega, first Peruvian-born person in space (N)
-
Oleg Novitskiy (N)
-
Lisa Nowak (N)
-
Karen Nyberg (N)
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Bryan O'Connor (O)
-
Ellen Ochoa, first Hispanic woman in space (O)
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Wubbo Ockels (1946–2014), first Dutch citizen in space (O)
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William Oefelein (O)
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John D. Olivas (O)
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Gregory Olsen, third spaceflight participant (O)
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Takuya Onishi (O)
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Ellison Onizuka (1946–1986), died in the Space Shuttle Challenger disaster (O)
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Yuri Onufrienko (O)
-
Stephen Oswald (O)
-
Aleksey Ovchinin (O)
-
Robert Overmyer (1936–1996) (O)
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Gennady Padalka, as of 2015, has spent longer in space than any other person, at 879.48 days over five flights (P)
-
William Pailes (P)
-
Scott Parazynski (P)
-
Ronald A. Parise (1951–2008) (P)
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Robert Parker (P)
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Luca Parmitano (P)
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Nicholas Patrick (P)
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Viktor Patsayev (1933–1971), died during Soyuz 11 (P)
-
James Pawelczyk (P)
-
Julie Payette (P)
-
Gary Payton, first military astronaut (P)
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Tim Peake (P)
-
Philippe Perrin, first Morocco-born man in space (P)
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Thomas Pesquet (P)
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Donald Peterson (P)
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Donald Pettit (P)
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Pham Tuân, first Vietnamese and first Asian in space (P)
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John Phillips (P)
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William Pogue (1930–2014) (P)
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Alan G. Poindexter (1961–2012) (P)
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Mark Polansky (P)
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Alexander Poleshchuk (P)
-
Valeri Polyakov, holds record for single longest spaceflight, 437 days (P)
-
Marcos Pontes, first Brazilian in space (P)
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Leonid Popov (P)
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Pavel Popovich (1930–2009), first Ukrainian-born person in space (P)
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Charles Precourt (P)
-
Sergey Prokopyev (P)
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Dumitru Prunariu, first Romanian in space (P)
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Ilan Ramon (1954–2003), first Israeli in space; died on February 1, 2003, in the Space Shuttle Columbia disaster of STS-107 (R)
-
William Readdy (R)
-
Kenneth Reightler (R)
-
James F. Reilly (R)
-
Garrett Reisman (R)
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Thomas Reiter, first German to walk in space and first ESA astronaut to stay on the ISS (R)
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Vladimír Remek, first Czechoslovak and first non-Soviet European in space (R)
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Judith Resnik (1949–1986), died in the Space Shuttle Challenger disaster (R)
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Sergei Revin (R)
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Paul W. Richards (R)
-
Richard N. Richards (R)
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Sally Ride (1951–2012), first American woman in space (R)
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Stephen Robinson (R)
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Roman Romanenko (R)
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Yury Romanenko (R)
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Kent Rominger (R)
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Stuart Roosa (1933–1994), flew on Apollo 14 (R)
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Jerry L. Ross, flew on seven space flights (R)
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Valery Rozhdestvensky (R)
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Kathleen Rubins (R)
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Nikolay Rukavishnikov (1932–2002) (R)
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Mario Runco, Jr. (R)
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Sergey Ryazansky (R)
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Valery Ryumin (R)
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Sergey Nikolayevich Ryzhikov (R)
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Albert Sacco (S)
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David Saint-Jacques (S)
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Aleksandr Samokutyayev (S)
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Gennadi Sarafanov (1942–2005) (S)
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Robert Satcher (S)
-
Viktor Savinykh (S)
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Svetlana Savitskaya, first woman to walk in space, first woman to visit a space station, first woman to travel to space twice (S)
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Wally Schirra (1923–2007) (S)
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Hans Schlegel (S)
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Harrison Schmitt, flew on Apollo 17 (S)
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Rusty Schweickart (S)
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Dick Scobee (1939–1986), died in the Space Shuttle Challenger disaster (S)
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David Scott (S)
-
Winston Scott (S)
-
Paul Scully-Power (S)
-
Richard A. Searfoss (S)
-
Margaret Rhea Seddon (S)
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Ronald M. Sega (S)
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Shneur Shimonov (S)
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Piers Sellers (1955–2016) (S)
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Aleksandr Serebrov (S)
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Yelena Serova (S)
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Vitaly Sevastyanov (S)
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Yuri Shargin, first Russian military cosmonaut (S)
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Salizhan Sharipov, first Kyrgyzstan-born man in space (S)
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Rakesh Sharma, first Indian in space (S)
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Helen Sharman, first Briton in space (S)
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Vladimir Shatalov, first Kazakhstan-born man in space (S)
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Brewster Shaw (S)
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Alan Shepard (1923–1998), first American in space (S)
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William Shepherd (S)
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Anton Shkaplerov (S)
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Sheikh Muszaphar Shukor, first Malaysian in space (S)
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Georgy Shonin (1935–1997) (S)
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Loren Shriver (S)
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Mark Shuttleworth, second spaceflight participant and first South African in space (S)
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Charles Simonyi, fifth spaceflight participant; second Hungarian in space after Bertalan Farkas (S)
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Oleg Skripochka (S)
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Aleksandr Skvortsov (S)
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Donald "Deke" Slayton (1924–1993), a Mercury astronaut (S)
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Steven Smith (S)
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Anatoly Solovyev, first Latvian-born man in space (S)
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Vladimir Solovyov (S)
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Sherwood Spring (S)
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Robert Springer (S)
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Thomas P. Stafford (S)
-
Heidemarie Stefanyshyn-Piper (S)
-
Robert Stewart (S)
-
Nicole Stott (S)
-
Gennadi Strekalov (1940–2004) (S)
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Frederick Sturckow (S)
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Kathryn D. Sullivan, first American woman to walk in space (S)
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Maksim Surayev (S)
-
Steven Swanson (S)
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John "Jack" Swigert (1931–1982), flew on Apollo 13 (S)
-
Arnaldo Tamayo Méndez, the first Cuban and the first person from a country in the Western Hemisphere other than the U.S. to travel to space; first Hispanophone and first person of African ancestry in space (T)
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Daniel Tani (T)
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Joseph Tanner (T)
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Evgeny Tarelkin (T)
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Valentina Tereshkova, first and youngest woman in space, only woman to travel solo (T)
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Norman Thagard (T)
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Gerhard Thiele (T)
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Robert Thirsk (T)
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Andrew Thomas, first Australian-born astronaut (T)
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Donald Thomas (T)
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Kathryn C. Thornton, first woman to make multiple EVAs (T)
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William Thornton (T)
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Pierre Thuot (T)
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Scott Tingle (T)
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Dennis Tito, first self-funded spaceflight participant (T)
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Gherman Titov (1935–2000), the second person to orbit the Earth, first to stay up for a day and the youngest person to make a spaceflight (T)
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Vladimir Titov (T)
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Michel Tognini (T)
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Valeri Tokarev (T)
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Sergei Treshchov (T)
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Eugene H. Trinh, first Vietnamese-American in space (T)
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Richard H. Truly (T)
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Bjarni Tryggvason, first Iceland-born man in space (T)
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Vasily Tsibliyev (T)
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Mikhail Tyurin (T)
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Yury Usachov (U)
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Ivan Vagner (V)
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Lodewijk van den Berg, first Dutch-born astronaut (V)
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James "Ox" van Hoften (V)
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Mark T. Vande Hei (V)
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Vladimir Vasyutin (1952–2002) (V)
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Charles L. Veach (1944–1995) (V)
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Franz Viehböck, first Austrian in space (V)
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Aleksandr Viktorenko (V)
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Pavel Vinogradov (V)
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Terry W. Virts (V)
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Roberto Vittori (V)
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Igor Volk (V)
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Alexander Volkov (V)
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Sergey Volkov, first second-generation astronaut or cosmonaut in space; son of Alexander Volkov (V)
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Vladislav Volkov (1935–1971), died on Soyuz 11 (V)
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Boris Volynov, first Jewish person in space (V)
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James S. Voss (V)
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Janice E. Voss (V)
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Koichi Wakata (W)
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Rex Walheim (W)
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Charles Walker (W)
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David M. Walker (1944–2001) (W)
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Joseph A. Walker (1921–1966), earliest born person in space, and first person to enter space twice; suborbital flights only (W)
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Shannon Walker – Soyuz TMA-19 (W)
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Ulrich Walter (W)
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Carl E. Walz (W)
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Taylor Wang, first ethnic Chinese person in space (W)
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Wang Yaping (W)
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Mary Weber (W)
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Paul Weitz (1932–2017) (W)
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James Wetherbee (W)
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Ed White (1930–1967), first American to "walk in space" (make an EVA); died in the Apollo 1 disaster (W)
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Douglas H. Wheelock (W)
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Peggy Whitson, longest single space flight by a woman, greatest total time in space by a woman, most EVAs and most time spent on EVA by a woman (W)
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Terrence Wilcutt (W)
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Dafydd Williams (W)
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Donald Williams (1942–2016) (W)
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Jeffrey Williams (W)
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Sunita "Suni" Williams (W)
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Barry Wilmore (W)
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Stephanie Wilson (W)
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Gregory R. Wiseman (W)
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Peter Wisoff (W)
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David Wolf (W)
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Alfred Worden (W)
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Naoko Yamazaki (Y)
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Yang Liwei, first Chinese national in space (Y)
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Boris Yegorov (1937–1994) (Y)
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Aleksei Yeliseyev (Y)
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Yi So-yeon, first South Korean in space (Y)
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John Young (1930–2018), flew on two Gemini, two Apollo (Apollo 10 and Apollo 16), and two Space Shuttle missions (Y)
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Kimiya Yui (Y)
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Fyodor Yurchikhin, first Georgian-born man in space (Y)
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Sergei Zalyotin (Z)
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George D. Zamka (Z)
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Zhai Zhigang, first Chinese person to walk in space (Z)
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Zhang Xiaoguang (Z)
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Vitaly Zholobov (Z)
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Vyacheslav Zudov (Z)
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