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Annette A. Aguilar, American percussionist, bandleader, and music educator (List)
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Horacio Aguirre Baca, founder of Diario Las Americas of Miami, Florida (List)
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Roberto Aguirre-Sacasa, American playwright, screenwriter and comic-book writer (List)
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Patrick Argüello, considered a martyr of the Popular Front for the Liberation of Palestine (List)
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Marvin Benard, Major League Baseball player (List)
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Maurice Benard, actor on American soap operas All My Children and General Hospital (List)
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Carolina Bermudez, radio personality on Elvis Duran and the Morning Show in New York on WHTZ (List)
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Claudia Bermúdez, politician, ran for the United States Congress (List)
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Bella Blue, burlesque dancer (List)
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T-Bone, rapper (List)
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Randy Caballero, undefeated Nicaraguan American professional boxer in the Featherweight division (List)
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Róger Calero, ran for U.S. President in the 2004 elections* (List)
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Barbara Carrera, Nicaraguan-born American film and television actress (List)
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Oswaldo Castillo, gardener/construction worker-turned-actor. (List)
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Michael Cordúa, restaurateur, entrepreneur, businessman, award winning self-taught chef (List)
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DJ Craze, only DJ in history to win 3 consecutive World DMC Champion titles (List)
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Miguel D'Escoto, Roman Catholic priest and former foreign minister (List)
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Omar D'Leon, painter and poet (List)
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Salomón de la Selva, poet, author of Tropical Town and Other Poems (List)
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Edward'O, astronalyst and co-host of 12 Corazones (List)
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Bill Guerin, NHL player (mother from Nicaragua) (List)
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Ricardo Hurtado, American actor (School of Rock) (List)
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Bianca Jagger, human rights advocate and ex-wife of Mick Jagger (List)
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Diana López, Olympic bronze medalist in the sport of taekwondo (List)
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Mark López, Olympic silver medalist in the sport of taekwondo (List)
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Steven López, two time Olympic gold medalist in the sport of taekwondo (List)
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Dennis Martínez, first Nicaraguan-American to be a major league baseball pitcher or player (List)
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Camilo Mejía, former Staff Sergeant of the Florida National Guard and anti-war activist (List)
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Tony Meléndez, singer, composer, writer and musician who was born with no arms (List)
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Christianne Meneses Jacobs, publisher of the U.S.'s only Spanish-language children's magazine (List)
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Franck de Las Mercedes, painter (List)
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Ana Navarro, Republican strategist and political commentator (List)
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David Obregon, professional boxer (List)
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Horacio Peña, professor, writer, and poet (List)
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Claudia Poll, Nicaraguan born swimmer (List)
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Silvia Poll, Nicaraguan born swimmer (List)
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Hope Portocarrero, former First Lady of Nicaragua (1967–1972) (List)
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Anastasio Somoza Portocarrero, son of former Nicaraguan president Anastasio Somoza Debayle and Hope Portocarrero de Somoza (List)
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James Quesada, anthropologist and professor (List)
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Mari Ramos, weather anchor for CNN (List)
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Michele Richardson, competition swimmer and Olympic silver medalist (List)
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Tammy Rivera, singer and television personality (List)
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J Smooth, bilingual hip hop and reggaeton singer (List)
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Hilda Solis, U.S. congresswoman. She is of Mexican and Nicaraguan descent (List)
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Eve Torres, professional wrestler with WWE (List)
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Torombolo, reggaeton singer (List)
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Gabriela Revilla, Writer, Producer, Director (List)
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Gabriel Traversari, actor, director, writer, singer, songwriter and painter (List)
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Guillermo Wagner Granizo (1923–1995), ceramic tile muralist in Northern California, his mother was from Nicaragua. (List)
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Donald Vega, jazz musician and composer (List)
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Benny Urquidez, kickboxer, martial arts choreographer. His father was born in Granada, Nicaragua. (List)
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